This Task Book is an online database of research projects supported by NASA's Biological & Physical Sciences (BPS) Division and Human Research Program. Beginning in October 2017, the Task Book has included projects within the Translational Research Institute for Space Health (TRISH). The Task Book database also covers BPS projects in the Established Program to Stimulate Competitive Research (EPSCoR) from October 2020 to the present. Completed investigations under the National Space Biomedical Research Institute (NSBRI) may also be found in the Task Book.

Visitors to the NASA Task Book can view project descriptions, annual progress, final reports, and bibliographical listings of publications resulting from NASA-funded studies in Space Biology, Physical Sciences, and Human Research. Visitors can also learn about the potential impact of these studies and the anticipated benefits that such research could offer to Earth.

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Sex-Specific Physiological and Transcriptomic CNS Responses to Combined Effects of Spaceflight Stressors in Drosophila melanogaster. Image courtesy of NASA Ames Research Center and NASA Task Book. This project aims to investigate how temporal light quality or intensity alternation during different growth phases influences the growth and nutritional quality of red-leaf lettuce grown under superelevated CO2 stress. Courtesy of Qingwu Meng, University of Delaware and NASA Task Book. This image shows brain tissue enhancement at various time delays after gadolinium contrast injection. This is the current gold standard approach for studying glymphatic function in human participants. Source : Richmond et al. (2023). Quantification approaches for magnetic resonance imaging following... Clonal hematopoiesis (CH) occurs when blood cells harboring an advantageous mutation propagate faster than others. These mutations confer a risk for hematological cancers and cardiovascular disease, and can sometimes be related to spaceflight (right), and then propagate into more abundant cell popul... Micro computerized tomography (uCT) scout view scan of an E18 fetus. Credit: H. Allaway. Courtesy image submitted to Task Book. Eosin-stained rodent bone microscopy slide for assessment of marrow adipose tissue. The slide was viewed using BioQuant Osteo software with a 20x microscope lens. Credit: H. Allaway. Courtesy image submitted to Task Book. Courtesy image submitted to Task Book. Courtesy image submitted to Task Book. Courtesy image submitted to Task Book. Credit: Lunar and Planetary Institute/Universities Space Research Association (USRA) Courtesy image submitted to Task Book.