This Task Book is an online database of research projects supported by NASA's Biological & Physical Sciences (BPS) Division and Human Research Program. Beginning in October 2017, the Task Book has included projects within the Translational Research Institute for Space Health (TRISH). The Task Book database also covers BPS projects in the Established Program to Stimulate Competitive Research (EPSCoR) from October 2020 to the present. Completed investigations under the National Space Biomedical Research Institute (NSBRI) may also be found in the Task Book.

Visitors to the NASA Task Book can view project descriptions, annual progress, final reports, and bibliographical listings of publications resulting from NASA-funded studies in Space Biology, Physical Sciences, and Human Research. Visitors can also learn about the potential impact of these studies and the anticipated benefits that such research could offer to Earth.

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Courtesy image submitted to Task Book. Closeup of the fungal spores (called conidia) on a squash leaf. Courtesy image submitted to Task Book. Macroscopic view of a powdery mildew (PM) colony on the lab host plant, squash. Squash are used to maintain pure cultures of the obligate phytopathogen. Courtesy image submitted to Task Book. Identifying high-yielding, high-nutrient cultivars of mizuna and related varieties. Photo credit: Kellie Walters. Courtesy image submitted to Task Book. Invertebrate Gravitational Continuum Experiment (iGCE) will compare the effects of four gravities (Earth, martian, lunar, and microgravity) on two different genetic model systems, Drosophila and C. elegans. We will look at changes in the nervous system and in muscle in both species and identify the ... Courtesy image submitted to Task Book. Palmer Station, Antarctica. Courtesy image submitted to Task Book. By leveraging a metabolic modeling framework and engineered budding yeast strains, our goal is to perform the ground testing necessary to validate strains that yield distinct responses to specific stressors, both laying the groundwork for a potential lunar surface mission and improving the usefulnes... Visual summary of hypotheses tested in this study. In a Rotating Wall Vessel bioreactor designed to mimic microgravity for microbial cell culture, different rotation rates induce different fluid environments on a continuum between well-mixed and diffusion-limited (axis at left). We use a well-unders... Plants respond to changes in their environment by changing the patterns of gene expression. These changes become a readout of the adaptive response, and can be evaluated biochemically with RNA sequencing, and also visually by examining the tissue-specific expression of genes engineered to express fl...