Responsible Center: NASA JSC
Grant Monitor: Norsk, Peter
Center Contact: Peter.norsk@nasa.gov
Unique ID: 8763
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Solicitation / Funding Source: 2010 Crew Health NNJ10ZSA003N
Grant/Contract No.: NNX12AF04G
Project Type: FLIGHT
Flight Program: ISS
TechPort: No |
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Human Research Program Elements: |
(1) HHC:Human Health Countermeasures
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Human Research Program Risks: |
(1) Muscle:Risk of Impaired Performance Due to Reduced Muscle Size, Strength and Endurance
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Human Research Program Gaps: |
(1) M24:Characterize the time course of changes in muscle protein turnover, muscle mass, and function during long duration space flight.
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Flight Assignment/Project Notes: |
ISS |
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Task Description: |
Muscle size, structure, and coordination changes during spaceflight are likely triggered by absent or reduced loading of receptors in the soles of the feet and the muscles and joints of the lower limbs. To better understand the physiological bases of these adaptive responses, we propose to examine, in-flight, the relationships between lower limb loading and muscle activation, and control. The proposed experiments will study astronaut volunteers before flight and on multiple occasions during flight using the MARES device to provide loading to the feet and legs as well as device that can apply pressure to the soles of the feet. The effects on muscle activation and performance associated with foot pressure alone or foot pressure plus lower limb loading will be investigated. If successful this investigation will provide new insight into the role of lower extremity load receptors in modulating muscle function and new evidence regarding the potential for a passive loading countermeasure to attenuate the undesirable side effects of space flight on muscle function. |
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Research Impact/Earth Benefits: |
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