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Project Title:  Mars Adaptive Training Integrative Knowledge System (MATRIKS) to Improve Operational Performance and Its Neural Basis for Spaceflight Reduce
Images: icon  Fiscal Year: FY 2022 
Division: Human Research 
Research Discipline/Element:
HRP HFBP:Human Factors & Behavioral Performance (IRP Rev H)
Start Date: 12/17/2021  
End Date: 03/31/2026  
Task Last Updated: 04/14/2022 
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Principal Investigator/Affiliation:   Stahn, Alexander  Ph.D. / University of Pennsylvania 
Address:  Division of Sleep and Chronobiology, Department of Psychiatry 
423 Guardian Dr, 1016 Blockley Hall 
Philadelphia , PA 19104-4865 
Email: astahn@pennmedicine.upenn.edu 
Phone: 215-898-9667  
Congressional District:
Web:  
Organization Type: UNIVERSITY 
Organization Name: University of Pennsylvania 
Joint Agency:  
Comments:  
Co-Investigator(s)
Affiliation: 
Basner, Mathias  M.D., Ph.D. University of Pennsylvania 
Dinges, David  Ph.D. University of Pennsylvania 
Gur, Ruben  Ph.D. The Trustees of the University of Pennsylvania 
Johannes, Bernd  Ph.D. Deutsches Zentrum Fuer Luft- Und Raumfahrt E.V, Germany 
Kuehn, Simone  Ph.D. Max Planck Institute for Human Development, Berlin, Germany 
Piechowski, Sarah  M.S. Deutsches Zentrum Fuer Luft- Und Raumfahrt E.V, Germany 
Roalf, David  Ph.D. University of Pennsylvania 
Roma, Peter  Ph.D. NASA Johnson Space Center 
Whiting, Sara  Ph.D. NASA/Lyndon B Johnson Space Center 
Loerch, Linda  M.S. NASA Johnson Space Center 
Project Information: Grant/Contract No. 80NSSC22K0648 
Responsible Center: NASA JSC 
Grant Monitor: Whitmire, Alexandra  
Center Contact:  
alexandra.m.whitmire@nasa.gov 
Solicitation / Funding Source: 2020-2021 HERO 80JSC020N0001-HHP, OMNIBUS3 Human Research Program: Human Health & Performance Appendix E; Omnibus3-Appendix F 
Grant/Contract No.: 80NSSC22K0648 
Project Type: GROUND 
Flight Program:  
TechPort: No 
No. of Post Docs:  
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No. of Master's Candidates:  
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No. of Master's Degrees:  
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Human Research Program Elements: (1) HFBP:Human Factors & Behavioral Performance (IRP Rev H)
Human Research Program Risks: (1) Bmed:Risk of Adverse Behavioral Conditions and Psychiatric Disorders
(2) HFBP Team:Risk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team (IRP Rev J)
(3) HSIA:Risk of Adverse Outcome Due to Inadequate Human Systems Integration Architecture (IRP Rev L)
Human Research Program Gaps: (1) Team-105:We need to identify a set of countermeasures to support team function and enable multiple distributed teams to manage shifting levels of autonomy for all phases of increasingly earth independent, long duration exploration missions (IRP Rev L)
Flight Assignment/Project Notes: Note: End date changed to 03/31/2026 per NSSC information (Ed., 5/16/22).

Task Description: Future long-duration space expeditions will be one of the most difficult, dangerous, and dynamic operations in history, ranging from Earth orbit operations to planetary and universe exploration. With prolonged mission durations, spaceflight crews will become increasingly dependent on onboard technologies for knowledge acquisition and maintenance. It is expected that not all skills and knowledge required for these missions can be retained and retrieved based on pre-mission training alone. With the present proposal, we will target NASA’s particular interest in assessing a Mars Adaptive TRaining Integrative Knowledge System (MATRIKS) as a countermeasure that is based on scientific principles of learning, retention, and transfer that are most relevant to spaceflight operations. The system leverages a previously developed and validated workstation that simulates a rendezvous and docking maneuver using real spacecraft flight dynamics. It is designed to (1) train and improve sensorimotor skills relevant for inflight and post-landing operational tasks; (2) feature an autonomous and adaptive training approach that does not rely on feedback from flight operations on the ground; (3) maximize the transfer of mission-relevant motor skills; (4) allow the assessment of the neural circuitry underlying the task; and (5) deliver the training in a motivating and meaningful way to astronauts. Using NASA’s high-fidelity Human Exploration Research Analog (HERA) we will identify if, and to what extent, MATRIKS will improve operational performance using the NASA Robotics On-board Trainer for Research (ROBoT-r) and promote transfer to general cognitive performance (Cognition battery) and distinctive visuo-spatial tasks critical for telerobotic tasks (Spatial Cognition battery). Using state-of-the-art multi-modal neuroimaging, we will also target NASA’s particular interest in assessing the brain structural changes and the neural circuitry of key brain networks expected to be relevant for spaceflight-related performance. By performing a subset of the MATRIKS spacecraft docking in the Magnetic Resonance Imaging (MRI) scanner, we will also be able to provide valuable information regarding NASA’s target in identifying the neural circuitry associated with operationally relevant tasks. The expected significance of this project relates to its relevance for facilitating effective countermeasure tools to acquire and retain operational skills that are critical for exploration class missions. The project is designed to be integrated into a Virtual NASA Specialized Center of Research (VNSCOR) promoting maximal synergies between the validation of the proposed adaptive training system, other countermeasures relevant to enhancing sensorimotor performance, and animal models applying an adaptive training program to stimulate motor performance and its neural circuitry. At the conclusion of the research, we will have (1) defined and demonstrated the use of a neuroscience-based, adaptive training integrative knowledge system to potentially mitigate visuo-spatial and sensorimotor brain changes associated with prolonged isolation and confinement to reduce the likelihood or impact of potential decrements in human performance capabilities during long-duration space missions; (2) performed an integrative assessment and testing of the adaptive visuo-motor training system based on meaningful tasks relevant to spaceflight in a high-fidelity spaceflight analog, and including the identification of potential interactions with other mission-relevant operational training procedures; and (3) identified specific brain structural and functional region changes in response to the proposed adaptive visuo-motor training program.

Research Impact/Earth Benefits:

Task Progress & Bibliography Information FY2022 
Task Progress: New project for FY 2022.

Bibliography Type: Description: (Last Updated: 02/16/2022) 

Show Cumulative Bibliography Listing
 
 None in FY 2022