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Articles in Peer-reviewed Journals
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Chang J, Luo Y, Wang Y, Pathak R, Sridharan V, Jones T, Mao XW, Nelson G, Boerma M, Hauer-Jensen M, Zhou D, Shao L. "Low doses of oxygen ion irradiation cause acute damage to hematopoietic cells in mice." PLoS One. 2016 Jul 1;11(7):e0158097. eCollection 2016. https://doi.org/10.1371/journal.pone.0158097 ; PubMed PMID: 27367604; PubMed Central PMCID: PMC4930193
, Jul-2016
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Articles in Peer-reviewed Journals
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Pathak R, Wang J, Garg S, Aykin-Burns N, Petersen KU, Hauer-Jensen M. "Recombinant thrombomodulin (Solulin) ameliorates early intestinal radiation toxicity in a preclinical rat model." Radiat Res. 2016 Aug;186(2):112-20. https://doi.org/10.1667/RR14408.1 ; PubMed PMID: 27459702; PubMed Central PMCID: PMC4995594 , Aug-2016
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Articles in Peer-reviewed Journals
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Wang Y, Boerma M, Zhou D. "Ionizing radiation-induced endothelial cell senescence and cardiovascular diseases." Radiat Res. 2016 Aug;186(2):153-61. Review. https://doi.org/10.1667/RR14445.1 ; PubMed PMID: 27387862; PubMed Central PMCID: PMC4997805
, Aug-2016
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Articles in Peer-reviewed Journals
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Boerma M. "An introduction to space radiation and its effects on the cardiovascular system." THREE. 2016 Oct 13:1-12. https://three.jsc.nasa.gov/articles/Boerma-Cardiovascular-and-IR.pdf
, Oct-2016
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Articles in Peer-reviewed Journals
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Chang J, Wang Y, Pathak R, Sridharan V, Jones T, Mao XW, Nelson G, Boerma M, Hauer-Jensen M, Zhou D, Shao L. "Whole body proton irradiation causes acute damage to bone marrow hematopoietic progenitor and stem cells in mice." Int J Radiat Biol. 2017 Dec;93(12):1312-20. Epub 2017 Aug 7. https://doi.org/10.1080/09553002.2017.1356941 ; PubMed PMID: 28782442 , Dec-2017
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Articles in Peer-reviewed Journals
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Kiffer F, Carr H, Groves T, Anderson JE, Alexander T, Wang J, Seawright JW, Sridharan V, Carter G, Boerma M, Allen AR. "Effects of 1H + 16O charged particle irradiation on short-term memory and hippocampal physiology in a murine model." Radiat Res. 2018 Jan;189(1):53-63. https://doi.org/10.1667/RR14843.1 ; PubMed PMID: 29136391 , Jan-2018
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Articles in Peer-reviewed Journals
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Wang Y, Chang J, Li X, Pathak R, Sridharan V, Jones T, Mao XW, Nelson G, Boerma M, Hauer-Jensen M, Zhou D, Shao L. "Low doses of oxygen ion irradiation cause long-term damage to bone marrow hematopoietic progenitor and stem cells in mice." PLoS One. 2017 Dec 12;12(12):e0189466. eCollection 2017. https://doi.org/10.1371/journal.pone.0189466 ; PubMed PMID: 29232383; PubMed Central PMCID: PMC5726652 , Dec-2017
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Articles in Peer-reviewed Journals
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Carr H, Alexander TC, Groves T, Kiffer F, Wang J, Price E, Boerma M, Allen AR. "Early effects of 16O radiation on neuronal morphology and cognition in a murine model." Life Sciences in Space Research. 2018 May;17:63-73. Epub 2018 Mar 14. https://doi.org/10.1016/j.lssr.2018.03.001 ; PubMed PMID: 29753415
, May-2018
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Articles in Peer-reviewed Journals
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Mao XW, Boerma M, Rodriguez D, Campbell-Beachler M, Jones T, Stanbouly S, Sridharan V, Wroe A, Nelson GA. "Acute effect of low-dose space radiation on mouse retina and retinal endothelial cells." Radiat Res. 2018 Jul;190(1):45-52. Epub 2018 May 9. https://doi.org/10.1667/RR14977.1 ; PubMed PMID: 29741442 , Jul-2018
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Articles in Peer-reviewed Journals
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Kiffer F, Howe AK, Carr H, Wang J, Alexander T, Anderson JE, Groves T, Seawright JW, Sridharan V, Carter G, Boerma M, Allen AR. "Late effects of 1H irradiation on hippocampal physiology." Life Sci Space Res (Amst). 2018 May;17:51-62. Epub 2018 Mar 15. https://doi.org/10.1016/j.lssr.2018.03.004 ; PubMed PMID: 29753414 , May-2018
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Articles in Peer-reviewed Journals
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Koturbash I. "2017 Michael Fry Award Lecture. When DNA is actually not a target: Radiation epigenetics as a tool to understand and control cellular response to ionizing radiation." Radiat Res. 2018 Jul;190(1):5-11. Epub 2018 Apr 26. https://doi.org/10.1667/RR15027.1 ; PubMed PMID: 29697303; PubMed Central PMCID: PMC6036898 , Jul-2018
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Articles in Peer-reviewed Journals
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Miousse IR, Ewing LE, Kutanzi KR, Griffin RJ, Koturbash I. "DNA methylation in radiation-induced carcinogenesis: Experimental evidence and clinical perspectives." Crit Rev Oncog. 2018;23(1-2):1-11. Review. https://doi.org/10.1615/CritRevOncog.2018025687 ; PubMed PMID: 29953365; PubMed Central PMCID: PMC6369919 , Jul-2018
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Articles in Peer-reviewed Journals
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Cheema AK, Byrum SD, Sharma NK, Altadill T, Kumar VP, Biswas S, Balgley BM, Hauer-Jensen M, Tackett AJ, Ghosh SP. "Proteomic changes in mouse spleen after radiation-induced injury and its modulation by gamma-tocotrienol." Radiat Res. 2018 Nov;190(5):449-63. Epub 2018 Aug 2. https://doi.org/10.1667/RR15008.1 ; PubMed PMID: 30070965; PubMed Central PMCID: PMC6297072
, Nov-2018
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Articles in Peer-reviewed Journals
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Mao XW, Boerma M, Rodriguez D, Campbell-Beachler M, Jones T, Stanbouly S, Sridharan V, Nishiyama NC, Wroe A, Nelson GA. "Combined effects of low-dose proton radiation and simulated microgravity on the mouse retina and the hematopoietic system." Radiat Res. 2019 Sep;192(3):241-50. Epub 2018 Nov 15. https://doi.org/10.1667/RR15219.1 ; PubMed PMID: 30430917 , Sep-2019
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Articles in Peer-reviewed Journals
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Howe A, Kiffer F, Alexander TC, Sridharan V, Wang J, Ntagwabira F, Rodriguez A, Boerma M, Allen AR. "Long-term changes in cognition and physiology after low-dose 16O irradiation." Int J Mol Sci. 2019 Jan 7;20(1):E188. https://doi.org/10.3390/ijms20010188 ; PubMed PMID: 30621014; PubMed Central PMCID: PMC6337104 , Jan-2019
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Articles in Peer-reviewed Journals
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Seawright JW, Sridharan V, Landes RD, Cao M, Singh P, Koturbash I, Mao XW, Miousse IR, Singh SP, Nelson GA, Hauer-Jensen M, Boerma M. "Effects of low-dose oxygen ions and protons on cardiac function and structure in male C57BL/6J mice." Life Sciences in Space Research. 2019 Feb;20:72-84. https://doi.org/10.1016/j.lssr.2019.01.003 ; PubMed PMID: 30797436; PubMed Central PMCID: PMC6391741 , Feb-2019
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Articles in Peer-reviewed Journals
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Kiffer F, Alexander T, Anderson JE, Groves T, Wang J, Sridharan V, Boerma M, Allen AR. "Late effects of 16O-particle radiation on female social and cognitive behavior and hippocampal physiology." Radiat Res. 2019 Mar;191(3):278-94. Epub 2019 Jan 21. https://doi.org/10.1667/RR15092.1 ; PubMed PMID: 30664396 , Mar-2019
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Articles in Peer-reviewed Journals
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Kiffer F, Boerma M, Allen A. "Behavioral effects of space radiation: A comprehensive review of animal studies." Life Sci Space Res (Amst). 2019 May;21:1-21. Epub 2019 Feb 19. Review. https://doi.org/10.1016/j.lssr.2019.02.004 ; PubMed PMID: 31101151 , May-2019
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Articles in Peer-reviewed Journals
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Miousse IR, Skinner CM, Sridharan V, Seawright JW, Singh P, Landes RD, Cheema AK, Hauer-Jensen M, Boerma M, Koturbash I. "Changes in one-carbon metabolism and DNA methylation in the hearts of mice exposed to space environment-relevant doses of oxygen ions (16O)." Life Sci Space Res. 2019 Aug;22:8-15. https://doi.org/10.1016/j.lssr.2019.05.003 ; PMID: 31421852; PMCID: PMC6703167
, Aug-2019
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Articles in Peer-reviewed Journals
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Kiffer F, Alexander T, Anderson J, Groves T, McElroy T, Wang J, Sridharan V, Bauer M, Boerma M, Allen A. "Late effects of 1H + 16O on short-term and object memory, hippocampal dendritic morphology and mutagenesis." Front Behav Neurosci. 2020 Jun 26;14:96. https://doi.org/10.3389/fnbeh.2020.00096 ; PMID: 32670032; PMCID: PMC7332779
, Jun-2020
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Articles in Peer-reviewed Journals
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Sridharan V, Seawright JW, Landes RD, Cao M, Singh P, Davis CM, Mao XW, Singh SP, Zhang X, Nelson GA, Boerma M. "Effects of single-dose protons or oxygen ions on function and structure of the cardiovascular system in male Long Evans rats." Life Sci Space Res (Amst). 2020 Aug;26:62-8. https://doi.org/10.1016/j.lssr.2020.04.002 ; PMID: 32718688; PMCID: PMC7387753 , Aug-2020
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Articles in Peer-reviewed Journals
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Upadhyay M, Rajagopal M, Gill K, Li Y, Bansal S, Sridharan V, Tyburski JB, Boerma M, Cheema AK. "Identification of plasma lipidome changes associated with low dose space-type radiation exposure in a murine model." Metabolites. 2020 Jun 17;10(6):E252. https://doi.org/10.3390/metabo10060252 ; PMID: 32560360; PMCID: PMC7345467 , Jun-2020
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Articles in Peer-reviewed Journals
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Swinton C, Kiffer F, McElroy T, Wang J, Sridharan V, Boerma M, Allen AR. "Effects of 16O charged-particle irradiation on cognition, hippocampal morphology and mutagenesis in female mice." Behav Brain Res. 2021 Jun 11;407:113257. https://doi.org/10.1016/j.bbr.2021.113257 ; PMID: 33794227
, Jun-2021
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Articles in Peer-reviewed Journals
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Nemec-Bakk AS, Sridharan V, Landes RD, Singh P, Cao M, Seawright JW, Liu X, Zheng G, Dominic P, Pathak R, Boerma M. "Mitigation of late cardiovascular effects of oxygen ion radiation by gamma-tocotrienol in a mouse model." Life Sci Space Res (Amst). 2021 Nov;31:43-50. https://doi.org/10.1016/j.lssr.2021.07.006 ; PubMed PMID: 34689949; PubMed PMCID: PMC8548672 , Nov-2021
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Articles in Peer-reviewed Journals
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Nemec-Bakk AS, Sridharan V, Landes RD, Singh P, Cao M, Dominic P, Seawright JW, Chancellor JC, Boerma M. "Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice." Life Sci Space Res (Amst). 2022 Feb;32:105-112. https://doi.org/10.1016/j.lssr.2021.12.004 ; PubMed PMID: 35065756; PubMed Central PMCID: PMC8803400 , Feb-2022
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Articles in Peer-reviewed Journals
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Nemec-Bakk AS, Sridharan V, Seawright JW, Nelson GA, Cao M, Singh P, Cheema AK, Singh B, Li Y, Koturbash I, Miousse IR, Ewing LE, Skinner CM, Landes RD, Lowery JD, Mao X-W, Singh SP, Boerma M. "Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model." Life Sci Space Res. 2023 May 1;37:78-87. https://doi.org/10.1016/j.lssr.2023.03.008 ; PMID: 37087182; PMCID: PMC10122719 , May-2023
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Articles in Peer-reviewed Journals
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Boerma M, Sridharan V, Mao XW, Nelson GA, Cheema AK, Koturbash I, Singh SP, Tackett AJ, Hauer-Jensen M. "Effects of ionizing radiation on the heart." Mutation Research. 2016 Oct - Dec;770(Pt B):319-27. Review. Epub 2016 Jul 10. https://doi.org/10.1016/j.mrrev.2016.07.003 ; PubMed PMID: 27919338; PubMed Central PMCID: PMC5144922 , Oct-2016
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Articles in Peer-reviewed Journals
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Casero D, Gill K, Sridharan V, Koturbash I, Nelson G, Hauer-Jensen M, Boerma M, Braun J, Cheema AK. "Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolome." Microbiome. 2017 Aug 18;5(1):105. https://doi.org/10.1186/s40168-017-0325-z ; PubMed PMID: 28821301; PubMed Central PMCID: PMC5563039 , Aug-2017
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Articles in Peer-reviewed Journals
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Jayabalan GS, Wu YK, Bille JF, Kim S, Mao XW, Gimbel HV, Rauser ME, Fan JT. "In vivo two-photon imaging of retina in rabbits and rats." Exp Eye Res. 2018 Jan;166:40-48. Epub 2017 May 5. https://doi.org/10.1016/j.exer.2017.04.009 ; PubMed PMID: 28483661 , Jan-2018
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Articles in Peer-reviewed Journals
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Koturbash I, Merrifield M, Kovalchuk O. "Fractionated exposure to low doses of ionizing radiation results in accumulation of DNA damage in mouse spleen tissue and activation of apoptosis in a p53/Atm-independent manner." Int J Radiat Biol. 2017 Feb;93(2):148-55. Epub 2016 Oct 19. https://doi.org/10.1080/09553002.2017.1231943 ;
PubMed PMID: 27758128 , Feb-2017
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Articles in Peer-reviewed Journals
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Mao XW, Nishiyama NC, Pecaut MJ, Campbell-Beachler M, Gifford P, Haynes KE, Becronis C, Gridley DS. "Simulated microgravity and low-dose/low-dose-rate radiation induces oxidative damage in the mouse brain." Radiation Research. 2016 Jun;185(6):647-57. https://doi.org/10.1667/RR14267.1 ; PubMed PMID: 27243749 , Jun-2016
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Articles in Peer-reviewed Journals
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Miousse IR, Chang J, Shao L, Pathak R, Nzabarushimana E, Kutanzi KR, Landes R, Tackett AJ, Hauer-Jensen M, Zhou D, Koturbash I. "Inter-strain differences in LINE-1 DNA methylation in the mouse hematopoietic system in response to exposure to low-doses of ionizing radiation." International Journal of Molecular Sciences. 2017 Jul 4;18(7):E1430. https://doi.org/10.3390/ijms18071430 ; PubMed PMID: 28677663; PubMed Central PMCID: PMC5535921 , Jul-2017
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Articles in Peer-reviewed Journals
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Miousse IR, Kutanzi KR, Koturbash I. "Effects of ionizing radiation on DNA methylation: from experimental biology to clinical applications." International Journal of Radiation Biology. 2017 May;93(5):457-69. Review. Epub 2017 Feb 21. https://doi.org/10.1080/09553002.2017.1287454 ; PubMed PMID: 28134023; PubMed Central PMCID: PMC5411327 , May-2017
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Articles in Peer-reviewed Journals
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Miousse IR, Tobacyk J, Melnyk S, James SJ, Cheema AK, Boerma M, Hauer-Jensen M, Koturbash I. "One-carbon metabolism and ionizing radiation: a multifaceted interaction." Biomolecular Concepts. 2017 May 24;8(2):83-92. Review. https://doi.org/10.1515/bmc-2017-0003 ; PubMed PMID: 28574375 , May-2017
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Articles in Peer-reviewed Journals
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Pathak R, Bachri A, Ghosh SP, Koturbash I, Boerma M, Binz RK, Sawyer JR, Hauer-Jensen M. "The vitamin E analog gamma-tocotrienol (GT3) suppresses radiation-induced cytogenetic damage." Pharmaceutical Research. 2016 Sep;33(9):2117-25. Epub 2016 May 23. https://doi.org/10.1007/s11095-016-1950-0 ; PubMed PMID: 27216753; PubMed Central PMCID: PMC4967083
, Sep-2016
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Articles in Peer-reviewed Journals
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Pathak R, Koturbash I, Hauer-Jensen M. "Detection of inter-chromosomal stable aberrations by multiple fluorescence in situ hybridization (mFISH) and spectral karyotyping (SKY) in irradiated mice." Journal of Visualized Experiments. 2017 Jan 11;(119):e55162. https://doi.org/10.3791/55162 ; PubMed PMID: 28117817; PubMed Central PMCID: PMC5352253 , Jan-2017
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Articles in Peer-reviewed Journals
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Prior S, Miousse IR, Nzabarushimana E, Pathak R, Skinner C, Kutanzi KR, Allen AR, Raber J, Tackett AJ, Hauer-Jensen M, Nelson GA, Koturbash I. "Densely ionizing radiation affects DNA methylation of selective LINE-1 elements." Environmental Research. 2016 Oct;150:470-81. Epub 2016 Jul 14. https://doi.org/10.1016/j.envres.2016.06.043 ; PubMed PMID: 27419368; PubMed Central PMCID: PMC5003736 , Oct-2016
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Articles in Peer-reviewed Journals
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Seawright JW, Samman Y, Sridharan V, Mao XW, Cao M, Singh P, Melnyk S, Koturbash I, Nelson GA, Hauer-Jensen M, Boerma M. "Effects of low-dose rate gamma-irradiation combined with simulated microgravity on markers of oxidative stress, DNA methylation potential, and remodeling in the mouse heart." PLoS One. 2017 Jul 5;12(7):e0180594. eCollection 2017. https://doi.org/10.1371/journal.pone.0180594 ; PubMed PMID: 28678877; PubMed Central PMCID: PMC5498037 , Jul-2017
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Awards
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Tackett A. (Alan Tackett) "Scharlau Family Endowed Chair, December 2016." Dec-2016
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Awards
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Boerma M. (Marjan Boerma) "Radiation Research Society J.W. Osborne Award, October 2016." Oct-2016
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Awards
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Hauer-Jensen M. (Martin Hauer-Jensen) "J. Thomas May Distinguished Endowed Chair, August 2016." Aug-2016
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