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July 15, 2011 Current Awareness

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The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Hada M, Zhang Y, Feiveson A, Cucinotta FA, Wu H. Association of inter- and intrachromosomal exchanges with the distribution of low- and high-LET radiation-induced breaks in chromosomes. Radiat Res. 2011 Jul;176(1):25-37. Epub 2011 Apr 5. (PIs: F.A. Cucinotta, H. Wu)
  2. Kennedy AR, Ware JH, Carlton W, Davis JG. Suppression of the later stages of radiation-induced carcinogenesis by antioxidant dietary formulations. Radiat Res. 2011 Jul;176(1):62-70. Epub 2011 Apr 26. (PI: A.R. Kennedy)
  3. Cucinotta FA, Chappell LJ. Updates to astronaut radiation limits: Radiation risks for never-smokers. Radiat Res. 2011 Jul;176(1):102-14. Epub 2011 May 16. (PI: F.A. Cucinotta)
  4. Huang Q, Li F, Liu X, Li W, Shi W, Liu FF, O'Sullivan B, He Z, Peng Y, Tan AC, Zhou L, Shen J, Han G, Wang XJ, Thorburn J, Thorburn A, Jimeno A, Raben D, Bedford JS, Li CY. Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy. Nat Med. 2011 Jul;17(7):860-6. (PI: C.Y. Li) Note: This article and the following article and an article in Science Signaling by CY Li investigate the role of caspases in regeneration of tissue arising out of apoptosis and cell reprogramming. The articles are summarized at the end of Li's NASA Task Book report. This Nature Medicine article shows that caspase 3 stimulates the regrowth of tumor cells during radiation treatment of tumors, a finding that may point the way to novel therapies in cancer treatment. There is a comment on this article in Nature Medicine News and Views.
  5. Li F, He Z, Shen J, Huang Q, Li W, Liu X, He Y, Wolf F, Li CY. Apoptotic caspases regulate induction of iPSCs from human fibroblasts. Cell Stem Cell. 2010 Oct 8;7(4):508-20. (PI: C.Y. Li) Note: This article, which may be obtained online without charge, is featured on the cover of the journal.
  6. Buonanno M, de Toledo SM, Azzam EI. Increased frequency of spontaneous neoplastic transformation in progeny of bystander cells from cultures exposed to densely ionizing radiation. PLoS One. 2011;6(6):e21540. Epub 2011 Jun 28. (PI: E.I. Azzam) Note: This article may be obtained online without charge.
  7. Domhan S, Ma L, Tai A, Anaya Z, Beheshti A, Zeier M, Hlatky L, Abdollahi A. Intercellular communication by exchange of cytoplasmic material via tunneling nano-tube like structures in primary human renal epithelial cells. PLoS One. 2011;6(6):e21283. Epub 2011 Jun 27. (PI: L.Hlatky/A. Abdollahi/NSCOR) Note: This article may be obtained online without charge.
  8. Bajaj A, Rosner B, Lockley SW, Schernhammer ES. Validation of a light questionnaire with real-life photopic illuminance measurements: The Harvard Light Exposure Assessment questionnaire. Cancer Epidemiol Biomarkers Prev. 2011 Jul;20(7):1341-9. (PI: S.W. Lockley)
  9. Iscla I, Wray R, Blount P. The oligomeric state of the truncated Mechanosensitive Channel of Large Conductance shows no variance in vivo. Protein Sci. 2011 Jul 7. [Epub ahead of print] (PI: P. Blount)
  10. Lopes N, Hawkins SA, Jegier P, Menn FM, Sayler GS, Ripp S. Detection of dichloromethane with a bioluminescent (lux) bacterial bioreporter. J Ind Microbiol Biotechnol. 2011 Jun 19. [Epub ahead of print] (PI: G.S. Sayler)
  11. Hodgson BD, Margolis DM, Salzman DE, Eastwood D, Tarima S, Williams LD, Sande JE, Vaughan WP, Whelan HT. Amelioration of oral mucositis pain by NASA near-infrared light-emitting diodes in bone marrow transplant patients. Support Care Cancer. 2011 Jul 3. [Epub ahead of print]

Other papers of interest:

  1. Sonne MP, H°jbjerre L, Alibegovic AC, Nielsen LB, Stallknecht BM, Vaag AA, Dela F. Endothelial function after 10 days of bed rest in individuals at risk for type 2 diabetes and cardiovascular disease. Exp Physiol. 2011 Jul 1. [Epub ahead of print] Note: Bed rest study.
  2. Thijssen DH, Green DJ, Hopman MT. Blood vessel remodeling and physical inactivity in humans. J Appl Physiol. 2011 Jul 7. [Epub ahead of print]
  3. Szostak J, Laurant P. The forgotten face of regular physical exercise: A 'natural' anti-atherogenic activity. Clin Sci (Lond). 2011 Aug;121(3):91-106.
  4. Pachon M JC, Pachon M EI, Cunha Pachon MZ, Lobo TJ, Pachon M JC, Santillana P TG. Catheter ablation of severe neurally meditated reflex (neurocardiogenic or vasovagal) syncope: Cardioneuroablation long-term results. Europace. 2011 Jun 28. [Epub ahead of print]
  5. Grover S. Skin in aviation and space environment. Indian J Dermatol Venereol Leprol. 2011 Jul-Aug;77(4):413-7. Note: The html version of this article may be obtained online without charge.
  6. GuÚguinou N, Bojados M, Jamon M, Derradji H, Baatout S, Tschirhart E, Frippiat JP, Legrand-Frossi C. Stress response and humoral immune system alterations related to chronic hypergravity in mice. Psychoneuroendocrinology. 2011 Jul 2. [Epub ahead of print]
  7. Ohira T, Terada M, Kawano F, Nakai N, Ogura A, Ohira Y. Region-specific responses of adductor longus muscle to gravitational load-dependent activity in Wistar Hannover rats. PLoS One. 2011;6(6):e21044. Epub 2011 Jun 22. Note: This article may be obtained online without charge.
  8. Novak ML, Bryer SC, Cheng M, Nguyen MH, Conley KL, Cunningham AK, Xue B, Sisson TH, You JS, Hornberger TA, Koh TJ. Macrophage-specific expression of urokinase-type plasminogen activator promotes skeletal muscle regeneration. J Immunol. 2011 Jun 27. [Epub ahead of print]
  9. Shadfar S, Couch ME, McKinney KA, Weinstein LJ, Yin X, Rodriguez JE, Guttridge DC, Willis M. Oral resveratrol therapy inhibits cancer-induced skeletal muscle and cardiac atrophy in vivo. Nutr Cancer. 2011 Jun 8:1. [Epub ahead of print]
  10. Beller G, Belavř DL, Sun L, Armbrecht G, Alexandre C, Felsenberg D. WISE-2005: Bed-rest induced changes in bone mineral density in women during 60 days simulated microgravity. Bone. 2011 Jun 24. [Epub ahead of print] Note: WISE-2005 bed rest study.
  11. Chang SH, Dudley-Javoroski S, Shields RK. Gravitational force modulates muscle activity during mechanical oscillation of the tibia in humans. J Electromyogr Kinesiol. 2011 Jun 25. [Epub ahead of print]
  12. Clin J, Aubin CE, Lalonde N, Parent S, Labelle H. A new method to include the gravitational forces in a finite element model of the scoliotic spine. Med Biol Eng Comput. 2011 Jul 5. [Epub ahead of print]
  13. Hooshmand S, Chai SC, Saadat RL, Payton ME, Brummel-Smith K, Arjmandi BH. Comparative effects of dried plum and dried apple on bone in postmenopausal women. Br J Nutr. 2011 May 31:1-8. [Epub ahead of print]
  14. Kim WK, Ke K, Sul OJ, Kim HJ, Kim SH, Lee MH, Kim HJ, Kim SY, Chung HT, Choi HS. Curcumin protects against ovariectomy-induced bone loss and decreases osteoclastogenesis. J Cell Biochem. 2011 Jul 5. [Epub ahead of print]
  15. Naharci I, Bozoglu E, Karadurmus N, Emer O, Kocak N, Kilic S, Doruk H, Serdar M. Vitamin B(12) and folic acid levels as therapeutic target in preserving bone mineral density (BMD) of older men. Arch Gerontol Geriatr. 2011 Jul 1. [Epub ahead of print]
  16. Hellweg CE, Baumstark-Khan C, Schmitz C, Lau P, Meier MM, Testard I, Berger T, Reitz G. Activation of the Nuclear Factor kappaB pathway by heavy ion beams of different linear energy transfer. Int J Radiat Biol. 2011 Jul 6. [Epub ahead of print]
  17. Monzen S, Takahashi K, Yoshino H, Kasai-Eguchi K, Kashiwakura I. Terminal maturation of megakaryocytes and platelet production by hematopoietic stem cells irradiated with heavy-ion beams. Radiat Res. 2011 Jul;176(1):8-16. Epub 2011 Apr 29.
  18. Li Q, Martinez JD. Loss of HSF1 results in defective radiation-induced G(2) arrest and DNA repair. Radiat Res. 2011 Jul;176(1):17-24. Epub 2011 May 10.
  19. Filiano AN, Fathallah-Shaykh HM, Fiveash J, Gage J, Cantor A, Kharbanda S, Johnson MR. Gene expression analysis in radiotherapy patients and C57BL/6 mice as a measure of exposure to ionizing radiation. Radiat Res. 2011 Jul;176(1):49-61. Epub 2011 Mar 1.
  20. Jeggo PA, Geuting V, L÷brich M. The role of homologous recombination in radiation-induced double-strand break repair. Radiother Oncol. 2011 Jul 5. [Epub ahead of print]
  21. Lysakowski A, Gaboyard-Niay S, Calin-Jageman I, Chatlani S, Price SD, Eatock RA. Molecular microdomains in a sensory terminal, the vestibular calyx ending. J Neurosci. 2011 Jul 6;31(27):10101-14. Note: This research is featured on the cover of the journal.
  22. Li X, von Holst H, Kleiven S. Influence of gravity for optimal head positions in the treatment of head injury patients. Acta Neurochir (Wien). 2011 Jul 8. [Epub ahead of print]
  23. Van Dongen HP, Belenky G, Vila BJ. The efficacy of a restart break for recycling with optimal performance depends critically on circadian timing. Sleep. 2011 Jul 1;34(7):917-29.
  24. Sugita S, Adachi T, Ueki Y, Sato M. A novel method for measuring tension generated in stress fibers by applying external forces. Biophys J. 2011 Jul 6;101(1):53-60.
  25. Zhang Q, Pettolino F, Dhugga KS, Rafalski A, Tingey S, Taylor J, Shirley N, Hayes K, Beatty M, Abrams SR, Zaharia LI, Burton RA, Bacic A, Fincher GB. Cell wall modifications in maize pulvini in response to gravitational stress. Plant Physiol. 2011 Jun 22. [Epub ahead of print] Note: This article may be obtained online without charge.
  26. Yang W, Marr LC. Dynamics of airborne influenza A viruses indoors and dependence on humidity. PLoS One. 2011;6(6):e21481. Epub 2011 Jun 24. Note: Interesting research, though not space life sciences. This article may be obtained online without charge.