This Task Book is an online database of research projects supported by NASA's Biological & Physical Sciences (BPS) Division and Human Research Program. Beginning in October 2017, the Task Book has included projects within the Translational Research Institute for Space Health (TRISH). The Task Book database also covers BPS projects in the Established Program to Stimulate Competitive Research (EPSCoR) from October 2020 to the present. Completed investigations under the National Space Biomedical Research Institute (NSBRI) may also be found in the Task Book.

Visitors to the NASA Task Book can view project descriptions, annual progress, final reports, and bibliographical listings of publications resulting from NASA-funded studies in Space Biology, Physical Sciences, and Human Research. Visitors can also learn about the potential impact of these studies and the anticipated benefits that such research could offer to Earth.

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Cross Section of Rat Cortical Bone prepared for Materials Characterization with Spherical Micro indentation. Image courtesy of Anthony Lau (PI) submitted to Task Book Bioengineered human brain microvasculature, consists of human brain endothelial cells (red), human brain pericytes (magenta) and human brain astrocytes (green). Courtesy image submitted to Task Book. Image courtesy of PI (Dr. Fernandez-Pello). Human mini-kidney structure grown from stem cells. Kidney tubular and filtering cells are labeled in different colors. Studying mini-kidney structures provides insights into possible effects of long-term space travel on human kidneys. Credit: Sophie Blackburn, Freedman Lab. Courtesy image submitted ... Spaceflight and Regolith Induced Mitochondrial Stress Mitigated by miRNA-based Countermeasures. (Courtesy image submitted to Task Book) Growth, physiology and nutrition dynamics of potato plants grown on lunar regolith simulant medium. Courtesy image submitted to Task Book. This project is exploring whether exposure to lunar dust simulants will alter the characteristics of human intestinal cells and intestinal-relevant bacteria in ways that could increase health risks. We will further evaluate if the combination of both lunar dust simulant and LSMMG culture of a model ... Credit: NASA (Courtesy images submitted to Task Book) The cyanobacterium Arthrospira platensis (common name spirulina) growing on lunar regolith simulant. Credit: Jared Broddrick. Image courtesy of J. Broddrick (PI). NASA Task Book Soleus muscles from adult, male Wistar rats exposed to 14 days of NL (normal loading, left) or HLS (hindlimb suspension, right) were stained with WGA lectin. Image courtesy of Xavier University and NASA Task Book.